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Unable to Replicate

This page includes a list, with additional information, on all studies that were awarded replications but that could not be completed due to an inability to obtain the necessary data and/or code to conduct the replication research.

Effect of Reduction in Household Air Pollution on Childhood Pneumonia in Guatemala (RESPIRE): A Randomised Controlled Trial

Replication Researcher: Jan Hattendorf
Original Paper Title: Effect of Reduction in Household Air Pollution on Childhood Pneumonia in Guatemala (RESPIRE): A Randomised Controlled Trial
Original Researchers:  Kirk R. Smith, John P. McCracken, Martin W. Weber, Alan Hubbard, Alisa Jenny, Lisa M. Thompson, John Balmes, Anaité Diaz, Byron Arana and Nigel Bruce
Original Publication: Lancet
Replication Plan: Not Applicable
Current Status: Unable to Replicate

Male Circumcision for HIV Prevention in Men in Rakai, Uganda: a Randomised Trial

Replication Researcher: Eric Djimeu
Original Paper Title: Male Circumcision for HIV Prevention in Men in Rakai, Uganda: a Randomised Trial
Original Researchers:  Ronald H. Gray, Godfrey Kigozi, David Serwadda, Frederick Makumbi, Stephen Watya, Fred Nalugoda, Noah Kiwanuka, Lawrence H. Moulton, Mohammad A. Chaudhary, Michael Z. Chen, Nelson K. Sewankambo, Fred Wabwire-Mangen, Melanie C. Bacon, Carolyn F.M. Williams, Pius Opendi, Steven J. Reynolds, Oliver Laeyendecker, Thomas C. Quinn and Maria J. Wawer
Original Publication: Lancet
Replication Plan:
Not Applicable
Current Status: Unable to Replicate

Prevention of HIV-1 Infection with Early Antiretroviral Therapy

Replication Researcher: Eric Djimeu
Original Paper Title: Prevention of HIV-1 Infection with Early Antiretroviral Therapy.
Original Researchers: Myron S. Cohen, Ying Q. Chen, Marybeth McCauley, Theresa Gamble, Mina C. Hosseinipour, Nagalingeswaran Kumarasamy, James G. Hakim, Johnstone Kumwenda, Beatriz Grinsztejn, Jose H.S. Pilotto, Sheela V. Godbole, Sanjay Mehendale, Suwat Chariyalertsak, Breno R. Santos, Kenneth H. Mayer, Irving F. Hoffman, Susan H. Eshleman, Estelle Piwowar-Manning, Lei Wang, Joseph Makhema, Lisa A. Mills, Guy de Bruyn, Ian Sanne, Joseph Eron, Joel Gallant, Diane Havlir, Susan Swindells, Heather Ribaudo, Vanessa Elharrar, David Burns, Taha E. Taha, Karin Nielsen-Saines, David Celentano, Max Essex and Thomas R. Fleming.
Original Publication: New England Journal of Medicine 
Replication Plan:
 Not Applicable 
Current Status: 
Unable to Replicate

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men 

Original Paper Title: Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
Original Researchers: Robert M. Grant, Javier R. Lama, Peter L. Anderson, Vanessa McMahan, Albert Y. Liu, Lorena Vargas, Pedro Goicochea, Martín Casapía, Juan Vicente Guanira-Carranza, Maria E. Ramirez-Cardich, Orlando Montoya-Herrera, Telmo Fernández, Valdilea G. Veloso, Susan P. Buchbinder, Suwat Chariyalertsak, Mauro Schechter, Linda-Gail Bekker, Kenneth H. Mayer, Esper Georges Kallás, K. Rivet Amico, Kathleen Mulligan, Lane R. Bushman, Robert J. Hance, Carmela Ganoza, Patricia Defechereux, Brian Postle, Furong Wang, J. Jeff McConnell, Jia-Hua Zheng, Jeanny Lee, James F. Rooney, Howard S. Jaffe, Ana I. Martinez, David N. Burns and David V. Glidden
Original Publication: New England Journal of Medicine
Replication Plan: Not Applicable
Current Status: Unable to Replicate

Effect of Early Versus Deferred Antiretroviral Therapy for HIV on Survival

Original Paper Title: Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival
Original Researchers: Mari M. Kitahata, Stephen J. Gange, Alison G. Abraham, Barry Merriman, Michael S. Saag, Amy C. Justice, Robert S. Hogg, Steven G. Deeks, Joseph J. Eron, John T. Brooks, Sean B. Rourke, M. John Gill, Ronald J. Bosch, Jeffrey N. Martin, Marina B. Klein, Lisa P. Jacobson, Benigno Rodriguez, Timothy R. Sterling, Gregory D. Kirk, Sonia Napravnik, Anita R. Rachlis, Liviana M. Calzavara, Michael A. Horberg, Michael J. Silverberg, Kelly A. Gebo, James J. Goedert, Constance A. Benson, Ann C. Collier, Stephen E. Van Rompaey, Heidi M. Crane, Rosemary G. McKaig, Bryan Lau, Aimee M. Freeman and Richard D. Moore
Original Publication: New England Journal of Medicine
Replication Plan: Not Applicable
Current Status: Unable to Replicate

Triple Antiretroviral Compared with Zidovudine and Single-Dose Nevirapine Prophylaxis During Pregnancy and Breastfeeding for Prevention of Mother-To-Child Transmission of HIV-1 (Kesho Bora study): a Randomized Controlled Tria

Original Paper Title: Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy and breastfeeding for prevention of mother-to-child transmission of HIV-1 (Kesho Bora study): a randomized controlled trial
Original Researchers: The Kesho Bora Study Group 
Original Publication: The Lancet Infectious Diseases
Replication Plan: Not Applicable
Current Status: Unable to Replicate