Replication Programme on HIV Prevention

3ie aims to improve the evidence base around HIV prevention and treatment in low- and middle-income countries. To this end, we funded five internal replications of influential or innovative impact evaluations of biomedical, behavioural, social, and structural HIV prevention and treatment interventions. Internal replication is the reconciliation and re-analysis of the findings of an original study using the study’s own raw data.

INTERFOTO, Alamy Stock Photo

Interventions include antiretroviral therapy, conditional cash transfers, country-level HIV treatment, and prevention and education programmes. If you have additional queries about this programme, please write to replication@3ieimpact.org.

Background

Three decades of work on HIV prevention have yielded a series of effective biomedical, behavioural and structural interventions among specific populations in small-scale settings and/or in randomized controlled trials. To date, few of them have been adopted at a population level to prevent HIV. Although most of them show clear potential for a major impact in reducing HIV and AIDS and the associated human and economic costs, the importance of the effort to prevent HIV and the magnitude of effort required to scale up any evidence-based intervention require the study results to be carefully reviewed, understood and confirmed.

Researchers conduct replications of an original study that is included in 3ie’s Impact Evaluation Repository. Accepted replications will be published as part of the 3ie Replication Paper Series. This programme is funded by the Gates Foundation.

Replication Researchers: Fang Yu, Nicholas A Hein and Danstan S Bagenda
Original Paper Title: The Regai Dzive Shiri Project: results of a randomised trial of an HIV prevention intervention for Zimbabwean youth
Original Researchers: Frances M Cowan and colleagues
Original Publication: Lancet
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Replication Researcher: Eric Djimeu
Original Paper Title: Timing of antiretroviral therapy for HIV-1 infection and tuberculosis 
Original Researchers: Diane V Havlir and colleagues
Original Publication: The New England Journal of Medicine
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Replication Researchers: Jiangtao Luo, Nicholas A Hein and Danstan S Bagenda
Original Paper Title: HIV development assistance and adult mortality in Africa
Original Researchers: Eran Bendavid and colleagues
Original Publication: JAMA
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Replication Researchers: Baojiang Chen and Morshed Alam
Original Paper Title: Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial  
Original Researchers: Lara Fairall and colleagues 
Original Publication: Lancet 
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Replication Researchers: Lynette M Smith, Nicholas A Hein and Danstan S Bagenda
Original Paper Title: Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi: a cluster randomized trial 
Original Researchers: Sarah Baird and colleagues
Original Publication: Lancet
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Related content

RP16

Preventing HIV and HSV-2 through improving knowledge and attitudes: a replication study of a multicomponent intervention in Zimbabwe

Replication paper 3ie 2018
Yu and colleagues conducted a replication study of an influential paper “The Regai Dzive Shiri Project: results of a randomised trial of an HIV prevention intervention for Zimbabwean youth” by Frances Cowan and colleagues.

PEPFAR and adult mortality: a replication study of HIV development assistance effects in Sub-Saharan African countries

PEPFAR and adult mortality: a replication study of HIV development assistance effects in Sub-Saharan African countries

Replication paper 3ie 2018
Nicholas Hein and colleagues conducted a replication of the 2012 publication HIV development assistance and adult mortality in Africa by Eran Bendavid and colleagues.

RP13

Stretching HIV treatment: A replication study of task shifting in South Africa

Replication paper 3ie 2017
Baojiang Chen and Morshed Alam conducted a replication study of Fairall and other’s influential paper, “Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH)”.

Cash transfers and HIV/HSV-2 prevalence: a replication of a cluster randomized trial in Malawi

Cash transfers and HIV/HSV-2 prevalence: a replication of a cluster randomized trial in Malawi

Replication paper 3ie 2017
In this paper, Lynette Smith, Nick Hein and Danstan Bagenda conduct a replication study of the influential 2012 publication, Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi.

There are no impact evaluations
There are no systematic reviews
There are no evidence gap maps
RP16

Preventing HIV and HSV-2 through improving knowledge and attitudes: a replication study of a multicomponent intervention in Zimbabwe

Replication paper 3ie 2018
Yu and colleagues conducted a replication study of an influential paper “The Regai Dzive Shiri Project: results of a randomised trial of an HIV prevention intervention for Zimbabwean youth” by Frances Cowan and colleagues.

PEPFAR and adult mortality: a replication study of HIV development assistance effects in Sub-Saharan African countries

PEPFAR and adult mortality: a replication study of HIV development assistance effects in Sub-Saharan African countries

Replication paper 3ie 2018
Nicholas Hein and colleagues conducted a replication of the 2012 publication HIV development assistance and adult mortality in Africa by Eran Bendavid and colleagues.

RP13

Stretching HIV treatment: A replication study of task shifting in South Africa

Replication paper 3ie 2017
Baojiang Chen and Morshed Alam conducted a replication study of Fairall and other’s influential paper, “Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH)”.

Cash transfers and HIV/HSV-2 prevalence: a replication of a cluster randomized trial in Malawi

Cash transfers and HIV/HSV-2 prevalence: a replication of a cluster randomized trial in Malawi

Replication paper 3ie 2017
In this paper, Lynette Smith, Nick Hein and Danstan Bagenda conduct a replication study of the influential 2012 publication, Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi.

There is no related content.